Bioinformatics generally applies computer science to solve biological problems. However, the field is interdisciplinary and constantly developing, so it is difficult to answer this question in one sentence. 2010-2011 articles have been archived. Earlier Archives are available.
General References
- PLos Computational Biology
The Roots of Bioinformatics (2011) PLoS Collections.
http://www.ploscollections.org/rootsofbioinformatics - Attwood TK, Gisel A, Eriksson N-E, Bongcam-Rudloff, E.
Concepts, historical milestones and the central place of bioinformatics in modern biology: a European perspective.
In Bioinformatics - Trends and Methodologies, M.A.Mahdavi Ed., Intech Online Publishers, November 2011
Intech Online Chapter
Selected Topics
- Eichler GS.
Bioinformatics/Biostatistics: microarray analysis.
Methods Mol Biol. 2012;823:347-58. PubMed abstract - Tucker A, Duplisea D.
Bioinformatics tools in predictive ecology: applications to fisheries.
Philos Trans R Soc Lond B Biol Sci. 2012 Jan 19;367(1586):279-90. PubMed abstract - Nitsche BM, Ram AF, Meyer V.
The use of open source bioinformatics tools to dissect transcriptomic data.
Methods Mol Biol. 2012;835:311-31. PubMed abstract - Allmer J.
Existing bioinformatics tools for the quantitation of post-translational modifications.
Amino Acids. 2012 Jan;42(1):129-38. PubMed abstract - Capriotti E, Nehrt NL, Kann MG, Bromberg Y.
Bioinformatics for personal genome interpretation.
Brief Bioinform. 2012 Jan 13. PubMed abstract - Scholz MB, Lo CC, Chain PS.
Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis.
Curr Opin Biotechnol. 2012 Feb;23(1):9-15. PubMed abstract - Ram PT, Mendelsohn J, Mills GB.
Bioinformatics and systems biology.
Mol Oncol. 2012 Feb 17. PubMed abstract - Sugimoto M, Kawakami M, Robert M, Soga T, Tomita M.
Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis.
Curr Bioinform. 2012 Mar;7(1):96-108. PubMed abstract - Wu D, Rice CM, Wang X.
Cancer bioinformatics: A new approach to systems clinical medicine.
BMC Bioinformatics. 2012 May 1;13(1):71. PubMed abstract - Altman RB.
Translational Bioinformatics: Linking the Molecular World to the Clinical World.
Clin Pharmacol Ther. 2012 May 2. PubMed abstract - Ouzounis CA.
Rise and demise of bioinformatics? Promise and progress.
PLoS Comput Biol. 2012 Apr;8(4):e1002487. PubMed abstract - Sharma V, Sarkar IN.
Bioinformatics opportunities for identification and study of medicinal plants.
Brief Bioinform. 2012 May 15. PubMed abstract - Scholz SW, Mhyre T, Ressom H, Shah S, Federoff HJ.
Genomics and bioinformatics of Parkinson's disease.
Cold Spring Harb Perspect Med. 2012 Jul;2(7):a009449. PubMed abstract - Hartler J, Tharakan R, Köfeler HC, Graham DR, Thallinger GG.
Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data.
Brief Bioinform. 2012 Jul 3. PubMed abstract - Manconi A, Vargiu E, Armano G, Milanesi L.
Literature Retrieval and Mining in Bioinformatics: State of the Art and Challenges.
Adv Bioinformatics. 2012;2012:573846. PubMed abstract - Valencia A, Hidalgo M.
Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics.
Genome Med. 2012 Jul 30;13(7):61. PubMed abstract - Logares R, Haverkamp TH, Kumar S, Lanzén A, Nederbragt AJ, Quince C, Kauserud H.
Environmental microbiology through the lens of high-throughput DNA sequencing: Synopsis of current platforms and bioinformatics approaches.
J Microbiol Methods. 2012 Jul 28. PubMed abstract - Furnham N, de Beer TA, Thornton JM.
Current challenges in genome annotation through structural biology and bioinformatics.
Curr Opin Struct Biol. 2012 Aug 9. PubMed abstract - Palma JP, Benitz WE, Tarczy-Hornoch P, Butte AJ, Longhurst CA.
Neonatal Informatics: Transforming Neonatal Care Through Translational Bioinformatics.
Neoreviews. 2012 May 1;13(5):e281-e284. PubMed abstract - Yan Q.
Translational bioinformatics in psychoneuroimmunology: methods and applications.
Methods Mol Biol. 2012;934:383-400. PubMed abstract - Fuellen G, Dengjel J, Hoeflich A, Hoeijmakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmítz U, Stolzing A, Sühnel J, Wuttke D, Vera J.
Systems Biology and Bioinformatics in Aging Research: A Workshop Report.
Rejuvenation Res. 2012 Sep 5. PubMed abstract - Malkaram SA, Hassan YI, Zempleni J.
Online tools for bioinformatics analyses in nutrition sciences.
Adv Nutr. 2012 Sep 1;3(5):654-65. PubMed abstract - Charoentong P, Angelova M, Efremova M, Gallasch R, Hackl H, Galon J, Trajanoski Z.
Bioinformatics for cancer immunology and immunotherapy.
Cancer Immunol Immunother. 2012 Sep 18. PubMed abstract - Bernt M, Braband A, Middendorf M, Misof B, Rota-Stabelli O, Stadler PF.
Bioinformatics Methods for the Comparative Analysis of Metazoan Mitochondrial Genome Sequences.
Mol Phylogenet Evol. 2012 Sep 27. pii: S1055-7903(12)00376-4. PubMed abstract - Mohabatkar H, Keyhanfar M, Behbahani M.
Protein Bioinformatics Applied to Virology.
Curr Protein Pept Sci. 2012 Oct 9. PubMed abstract - Fedorova ND, Moktali V, Medema MH.
Bioinformatics approaches and software for detection of secondary metabolic gene clusters.
Methods Mol Biol. 2012;944:23-45. PubMed abstract - Bellazzi R, Masseroli M, Murphy S, Shabo A, Romano P.
Clinical Bioinformatics: challenges and opportunities.
BMC Bioinformatics. 2012;13 Suppl 14:S1. PubMed abstract - Primig M.
The bioinformatics tool box for reproductive biology.
Biochim Biophys Acta. 2012 Dec;1822(12):1880-95. PubMed abstract - Fang X, Bai C, Wang X.
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome.
Clin Transl Med. 2012 Jun 9;1(1):9. PubMed abstract - Mulas F, Sacchi L, Zagar L, Garagna S, Zuccotti M, Zupan B, Bellazzi R.
Knowledge-based bioinformatics for the study of mammalian oocytes.
Int J Dev Biol. 2012;56(10-11-12):859-866. PubMed abstract
Links and references provided by Lynda Ellis